Description

1-(2,3-Dichlorophenyl)-3-(Trifluoromethyl)-1H-Pyrazole-5-Carbonitrile is a high-value, multi-functional heterocyclic compound featuring a pyrazole core substituted with dichlorophenyl, trifluoromethyl, and nitrile groups. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for agrochemical discovery. It is primarily sought by R&D and process development teams in the pharmaceutical and crop protection industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a core scaffold for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole and trifluoromethyl groups.
• Chemical Research & Development: Used as a specialized building block in medicinal chemistry and material science for creating libraries of compounds for high-throughput screening.
• Ligand and Catalyst Development: The nitrile and heterocyclic structure can be utilized to develop novel ligands for catalytic systems or metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(2,3-Dichlorophenyl)-3-(Trifluoromethyl)-1H-Pyrazole-5-Carbonitrile
CAS No.	1402585-36-7
Molecular Formula	C11H4Cl2F3N3
Molecular Weight	306.07 g/mol
Synonyms	1-(2,3-Dichlorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carbonitrile; 5-Cyano-1-(2,3-dichlorophenyl)-3-(trifluoromethyl)-1H-pyrazole; 1H-Pyrazole-5-carbonitrile, 1-(2,3-dichlorophenyl)-3-(trifluoromethyl)-; 1402585-36-7; 2,3-Dichloro-α,α,α-trifluoro-5-pyrazoleacetonitrile; 1-(2,3-Dichlorophenyl)-3-trifluoromethylpyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(2,3-Dichlorophenyl)-3-(Trifluoromethyl)-1H-Pyrazole-5-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity for critical R&D and scale-up processes. All materials are subjected to comprehensive analytical testing, including HPLC, GC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.