Description

n-[(8α,9S)-6'-Methoxycinchonan-9-Yl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is a sophisticated chiral thiourea derivative, synthesized from cinchona alkaloid and acetylated glucose precursors. This compound matters as a high-value organocatalyst and chiral selector, enabling precise asymmetric synthesis and enantiomeric separation critical for modern pharmaceutical development. It is primarily needed by research institutions and fine chemical manufacturers specializing in asymmetric catalysis, chiral resolution, and the synthesis of enantiomerically pure intermediates for active pharmaceutical ingredients (APIs).

Application

• Asymmetric Organocatalysis: Acts as a bifunctional catalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Chiral Stationary Phase (CSP) Precursor: Used in the development and manufacturing of high-performance liquid chromatography (HPLC) columns for enantiomer separation.
• Pharmaceutical Intermediate Synthesis: A key building block in the multi-step synthesis of complex, chiral drug candidates.
• Ligand for Metal Complexes: Serves as a chiral ligand to modify metal catalysts for asymmetric transformations.
• Academic & Industrial R&D: A valuable tool for methodological research in synthetic organic chemistry and process development.
• Analytical Reference Standard: Employed as a standard for method development and validation in chiral analysis.

Basic Information

Product Name	n-[(8α,9S)-6'-Methoxycinchonan-9-Yl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea
CAS No.	1402349-85-2
Molecular Formula	C35H43N3O10S
Molecular Weight	697.80 g/mol
Synonyms	(8α,9S)-6'-Methoxycinchonan-9-yl N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)carbamimidothioate; Cinchona Alkaloid Thiourea-Glucose Conjugate; 1-((8α,9S)-6'-Methoxycinchonan-9-yl)-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiourea; Chiral Thiourea Organocatalyst; Acetylated Glucopyranosyl Cinchona Thiourea; Asymmetric Synthesis Catalyst; Chiral Selector; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-[(8α,9S)-6'-Methoxycinchonan-9-Yl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is produced under strict quality management protocols suitable for research and development applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profile are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.