Description

4-Chloro-2-Methylquinoline-6-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both a halogenated quinoline core and a boronic acid functional group, makes it an indispensable reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as OLED emitters and charge-transport layers.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Academic & Industrial R&D: Essential for methodological development and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	4-Chloro-2-Methylquinoline-6-Boronic Acid
CAS No.	1402238-27-0
Molecular Formula	C₁₁H₁₁BClNO₂
Molecular Weight	235.47 g/mol
Synonyms	(6-Borono-4-chloro-2-methylquinoline); 4-Chloro-2-methyl-6-quinolineboronic acid; 2-Methyl-4-chloroquinoline-6-boronic acid; 4-Chloro-2-methylquinolin-6-ylboronic acid; Quinoline-6-boronic acid, 4-chloro-2-methyl-; B-(4-Chloro-2-methyl-6-quinolinyl)boronic acid; 1402238-27-0; 4-Chloro-2-methylquinoline-6-boronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Methylquinoline-6-Boronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures must be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.