Description

(E)-3-(5-Methoxy-1H-Indol-3-Yl)Acrylic Acid CAS NO 1402072-52-9 is a high-purity indole derivative featuring an acrylic acid moiety, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable, high-quality building block for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its bioactive indole core structure.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex organic molecules and specialty chemicals.
• Bioconjugation & Probe Development: The acrylic acid group enables coupling reactions for creating fluorescent probes or bioconjugates for diagnostic applications.
• Material Science Research: Investigated as a monomer or component in the development of advanced polymeric materials with specific optical or electronic properties.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and synthetic route exploration in academic and CRO laboratories.

Basic Information

Product Name	(E)-3-(5-Methoxy-1H-Indol-3-Yl)Acrylic Acid
CAS No.	1402072-52-9
Molecular Formula	C₁₄H₁₃NO₃
Molecular Weight	243.26 g/mol
Synonyms	(2E)-3-(5-Methoxy-1H-indol-3-yl)prop-2-enoic acid; (E)-3-(5-Methoxyindol-3-yl)acrylic Acid; 5-Methoxyindole-3-acrylic Acid; trans-3-(5-Methoxy-1H-indol-3-yl)acrylic Acid; 3-(5-Methoxy-1H-indol-3-yl)-2-propenoic acid; 5-Methoxy-1H-indole-3-acrylic acid; (E)-3-(5-Methoxy-1H-indol-3-yl)-2-propenoic acid
EINECS	Contact for details

Quality Control

Our (E)-3-(5-Methoxy-1H-Indol-3-Yl)Acrylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.