Description

tert-Butyl 1-Bromo-5-Oxo-7,8-Dihydroimidazo[1,5-C]Pyrimidine-6(5H)-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a reactive bromine substituent on a complex fused heterocyclic scaffold. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by R&D and process development teams in the pharmaceutical and biotechnology industries for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex heterocyclic compounds for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive bromine handle for further functionalization.
• API Synthesis: Employed in the development and scale-up of novel Active Pharmaceutical Ingredients (APIs), particularly those containing imidazopyrimidine cores.
• Chemical Biology Probes: Acts as a starting material for creating specialized probes and tool compounds used in biochemical and cellular assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	tert-Butyl 1-Bromo-5-Oxo-7,8-Dihydroimidazo[1,5-C]Pyrimidine-6(5H)-Carboxylate
CAS No.	1401983-71-8
Molecular Formula	C12H14BrN3O3
Molecular Weight	328.16 g/mol
Synonyms	1-Bromo-6-(tert-butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,5-c]pyrimidin-5-one; tert-Butyl 1-bromo-5-oxo-5,6,7,8-tetrahydroimidazo[1,5-c]pyrimidine-6-carboxylate; 6-(tert-Butoxycarbonyl)-1-bromo-5,6,7,8-tetrahydroimidazo[1,5-c]pyrimidin-5-one; 1-Bromo-6-Boc-5,6,7,8-tetrahydroimidazo[1,5-c]pyrimidin-5-one; 1401983-71-8; Imidazo[1,5-c]pyrimidine-6-carboxylic acid, 1-bromo-5-oxo-7,8-dihydro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Bromo-5-Oxo-7,8-Dihydroimidazo[1,5-C]Pyrimidine-6(5H)-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.