Description

3-(Hydroxymethyl)-1H-Pyrazole-5-Carboxylic Acid is a versatile heterocyclic building block featuring both a carboxylic acid and a hydroxymethyl functional group on a pyrazole core. This bifunctional structure makes it a critical intermediate for synthesizing more complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for constructing active ingredients and functional materials. The compound's reactivity allows for selective modifications, enabling the creation of targeted libraries for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic scaffold.
• Ligand and Chelator Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal complexation.
• Polymer and Material Science: Incorporated into polymer backbones or as a functional modifier to impart specific chemical properties to advanced materials.
• Bioconjugation and Probe Development: Utilized in life sciences for creating fluorescent probes, bioconjugates, and other diagnostic tools due to its modifiable functional groups.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing diverse heterocyclic compounds and complex molecular architectures.

Basic Information

Item	Detail
Product Name	3-(Hydroxymethyl)-1H-Pyrazole-5-Carboxylic Acid
CAS No.	1401555-38-1
Molecular Formula	C5H6N2O3
Molecular Weight	142.11 g/mol
Synonyms	5-(Hydroxymethyl)-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-5-carboxylic acid, 3-(hydroxymethyl)-; 3-Hydroxymethyl-1H-pyrazole-5-carboxylic acid; 5-Carboxy-1H-pyrazol-3-ylmethanol; Pyrazole-3,5-dicarboxylic acid 3-methyl ester (related); 3-(Hydroxymethyl)pyrazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(Hydroxymethyl)-1H-Pyrazole-5-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.