Description

1-(1-Methyl-1H-Pyrazol-4-Yl)Cyclopropanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclopropanamine core linked to a methylpyrazole moiety. This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing novel small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted drug candidates, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Synthesis: Used in the construction of potential kinase inhibitors due to the pyrazole pharmacophore.
• CNS Drug Candidates: Employed in the synthesis of compounds targeting neurological disorders.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Institutional Research: Used in university and institutional labs for chemical biology and therapeutic discovery.

Basic Information

Product Name	1-(1-Methyl-1H-Pyrazol-4-Yl)Cyclopropanamine Dihydrochloride
CAS No.	1401426-05-8
Molecular Formula	C7H12N3·2HCl
Molecular Weight	223.11 g/mol (Free base: 138.19 g/mol)
Synonyms	1-(1-Methyl-1H-pyrazol-4-yl)cyclopropanamine dihydrochloride; 1-(1-Methyl-1H-pyrazol-4-yl)cyclopropanamine hydrochloride (1:2); 1-(1-Methyl-1H-pyrazol-4-yl)cyclopropanamine HCl; 1-(1-Methyl-1H-pyrazol-4-yl)cyclopropanamine 2HCl; 1-(1-Methylpyrazol-4-yl)cyclopropanamine dihydrochloride; 1-Cyclopropyl-1-(1-methyl-1H-pyrazol-4-yl)methanamine dihydrochloride; 1401426-05-8.
EINECS	Contact for details

Quality Control

Our 1-(1-Methyl-1H-Pyrazol-4-Yl)Cyclopropanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.