Description

1-(Aminomethyl)-Cyclopropanemethanol Hcl is a high-purity, functionalized cyclopropane derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both aminomethyl and hydroxymethyl groups on a strained three-membered ring, makes it a versatile intermediate for constructing complex molecular architectures with enhanced biological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce conformational constraint and novel functionality into their target molecules.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs, antivirals, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring can improve metabolic stability and target binding.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The constrained cyclopropane scaffold is valuable for designing peptide mimics and bioisosteric replacements in medicinal chemistry.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Useful for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1-(Aminomethyl)-Cyclopropanemethanol Hcl
CAS No.	1400877-64-6
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(1-(Aminomethyl)cyclopropyl)methanol hydrochloride; Cyclopropanemethanol, 1-(aminomethyl)-, hydrochloride; 1-(Aminomethyl)cyclopropanemethanol hydrochloride; (1-(Aminomethyl)cyclopropyl)methanol HCl; Aminomethylcyclopropanemethanol HCl; CPMA-HCl
EINECS	Contact for details

Quality Control

Every batch of 1-(Aminomethyl)-Cyclopropanemethanol Hcl is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and cGMP manufacturing. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.