Description

tert-Butyl Methyl(3,4,5-Trifluoro-2-Nitrophenyl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoro and nitro-substituted aromatic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a key synthon for developing new-generation herbicides and pesticides that leverage the stability and bioavailability imparted by the fluorine atoms.
• Chemical Synthesis: Used in organic chemistry research for constructing complex molecules, exploiting the reactivity of the nitro group and the protective nature of the Boc (tert-butoxycarbonyl) group.
• Material Science: Potential application in the development of specialty polymers and advanced materials where fluorinated aromatic compounds are required for specific properties like chemical resistance or thermal stability.

Basic Information

Product Name	tert-Butyl Methyl(3,4,5-Trifluoro-2-Nitrophenyl)Carbamate
CAS No.	1400808-71-0
Molecular Formula	C13H15F3N2O4
Molecular Weight	320.27 g/mol
Synonyms	Carbamic acid, N-methyl-N-(3,4,5-trifluoro-2-nitrophenyl)-, 1,1-dimethylethyl ester; tert-Butyl N-methyl-N-(3,4,5-trifluoro-2-nitrophenyl)carbamate; Methyl(3,4,5-trifluoro-2-nitrophenyl)carbamic acid tert-butyl ester; Boc-Protected Methyl(3,4,5-Trifluoro-2-Nitroaniline); 1,1-Dimethylethyl methyl(3,4,5-trifluoro-2-nitrophenyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl Methyl(3,4,5-Trifluoro-2-Nitrophenyl)Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.