Description

(R)-(1-Tetrahydrofuran-3-Yl)Methanamine Hydrochloride is a high-purity chiral amine building block of significant importance in modern synthetic chemistry. Its value lies in its defined stereochemistry and functionalized tetrahydrofuran backbone, which are critical for constructing complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and antiviral compounds.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex molecules with high enantiomeric purity via chiral pool synthesis or as a precursor for chiral ligands and catalysts.
• Agrochemical Research: Used in the synthesis of advanced, stereospecific pesticides and herbicides where specific chirality can influence biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs within academic and industrial research laboratories.

Basic Information

Product Name	(R)-(1-Tetrahydrofuran-3-Yl)Methanamine Hydrochloride
CAS No.	1400744-17-3
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	(R)-3-(Aminomethyl)tetrahydrofuran hydrochloride; (R)-Tetrahydrofuran-3-ylmethanamine hydrochloride; (R)-(3-Tetrahydrofuryl)methylamine hydrochloride; (R)-Aminomethyl-tetrahydrofuran HCl; (R)-1-(Tetrahydrofuran-3-yl)methanamine HCl; (3R)-3-(Aminomethyl)oxolane hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(1-Tetrahydrofuran-3-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.