Description

Jwh 018 8-Quinolinyl Carboxamide is a synthetic cannabinoid receptor agonist research chemical with the CAS registry number 1400742-39-3. This compound is of significant interest in pharmacological and biochemical research for studying the endocannabinoid system and receptor interactions. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and analytical service providers for non-clinical investigative purposes.

Application

• Pharmacological Research: Used as a reference standard and active compound in studies targeting cannabinoid receptors (CB1 and CB2) to understand signaling pathways and physiological effects.
• Biochemical Assay Development: Serves as a key ligand in the development and validation of high-throughput screening assays for receptor binding and functional activity.
• Metabolic Pathway Analysis: Employed in in-vitro studies to investigate the metabolic stability, degradation pathways, and metabolite identification of synthetic cannabinoids.
• Forensic Science & Toxicology: Used as an analytical reference standard by forensic laboratories for the identification and quantification of novel psychoactive substances in compliance and legal cases.
• Academic Research: Supports university and institutional research into the structure-activity relationships (SAR) of quinolinyl carboxamide derivatives.
• Analytical Method Development: Acts as a critical component for developing and calibrating advanced analytical techniques such as LC-MS/MS, GC-MS, and HPLC for precise detection.

Basic Information

Product Name	Jwh 018 8-Quinolinyl Carboxamide
CAS No.	1400742-39-3
Molecular Formula	C24H23NO2
Molecular Weight	357.45 g/mol
Synonyms	1-Pentyl-3-(1-naphthoyl)indole; JWH-018; AM-678; 1-Pentyl-1H-indol-3-yl-1-naphthalenyl-methanone; 1-Pentyl-3-(1-naphthoyl)indole; Naphthalen-1-yl-(1-pentylindol-3-yl)methanone; JWH 018; AM678
EINECS	Contact for details

Quality Control

Our Jwh 018 8-Quinolinyl Carboxamide is manufactured under strict quality management protocols to ensure high purity and batch-to-batch consistency for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for research chemicals, and our QC process includes verification against authenticated reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to beige crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.