Description

(E)-1-(tert-Butylsulfinyl)-2,3-Dimethylbut-1-Ene is a high-value, chiral sulfinyl alkene building block used in advanced organic synthesis. This compound is critical for the stereoselective construction of complex molecules, offering precise control over three-dimensional architecture. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand & Catalyst Development: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the development of advanced organic materials with specific optoelectronic properties.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	(E)-1-(tert-Butylsulfinyl)-2,3-Dimethylbut-1-Ene
CAS No.	1400647-45-1
Molecular Formula	C10H20OS
Molecular Weight	188.33 g/mol
Synonyms	(E)-1-(tert-Butylsulfinyl)-2,3-dimethyl-1-butene; (E)-2,3-Dimethyl-1-[(2-methylpropan-2-yl)oxidosulfanyl]but-1-ene; tert-Butyl (E)-(2,3-dimethylbut-1-en-1-yl)sulfoxide; (E)-2,3-Dimethyl-1-(tert-butylsulfinyl)but-1-ene; Chiral Sulfinyl Alkene; Sulfoxide Building Block
EINECS	Contact for details

Quality Control

Our (E)-1-(tert-Butylsulfinyl)-2,3-Dimethylbut-1-Ene is manufactured under strict quality control protocols to ensure high chemical and chiral purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results from HPLC, GC, NMR, and chiral analysis. We adhere to cGMP principles where applicable to support our clients' regulatory requirements in advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain purity upon opening.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.