Description

1-(3-Bromophenyl)Cyclopropane-1-Carbohydrazide is a specialized organic building block featuring a cyclopropane ring and a carbohydrazide functional group. This compound is valued for its unique structural motif, which is critical for introducing conformational constraint and specific pharmacophores in advanced chemical synthesis. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the bromophenyl and constrained cyclopropane groups can modulate biological activity and selectivity.
• Chemical Biology Probe: Acts as a scaffold or a reactive handle in the design of molecular probes for studying enzyme function or protein-ligand interactions.
• Material Science Research: Investigated as a monomer or cross-linking agent for the development of specialty polymers with tailored thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct complex, multi-functional aromatic compounds.

Basic Information

Product Name	1-(3-Bromophenyl)Cyclopropane-1-Carbohydrazide
CAS No.	1400644-74-7
Molecular Formula	C10H11BrN2O
Molecular Weight	255.11 g/mol
Synonyms	1-(3-Bromophenyl)cyclopropanecarbohydrazide; 1-(3-Bromophenyl)cyclopropanecarboxylic acid hydrazide; 3-Bromo-α-(cyclopropylcarbonyl)benzenemethanamine; Cyclopropanecarbohydrazide, 1-(3-bromophenyl)-; 1400644-74-7; 1-(3-Bromophenyl)-1-cyclopropanecarbohydrazide
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenyl)Cyclopropane-1-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.