Description

(4-Fluorocyclohexyl)Methanamine HCl is a high-purity fluorinated amine hydrochloride salt, a valuable building block in advanced organic synthesis. Its core value lies in the strategic introduction of both a fluorine atom and a primary amine functional group, enabling precise molecular modifications for enhanced biological activity and physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, potentially in CNS, oncology, and metabolic disease research.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can improve stability, bioavailability, and activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers or advanced materials with specific surface properties.
• Chemical Biology Probes: Useful for incorporating a fluorine tag or an amine handle into molecules for imaging or proteomics studies.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring a fluorinated cyclohexylamine scaffold.

Basic Information

Product Name	(4-Fluorocyclohexyl)Methanamine HCl
CAS No.	1398503-96-2
Molecular Formula	C7H15ClFN
Molecular Weight	167.65 g/mol
Synonyms	(4-Fluorocyclohexyl)methanamine hydrochloride; 1-(Aminomethyl)-4-fluorocyclohexane hydrochloride; 4-Fluorocyclohexanemethylamine HCl; trans/cis-(4-Fluorocyclohexyl)methylamine hydrochloride; 4-Fluoro-cyclohexylmethylamine hydrochloride; (4-Fluoro-cyclohexyl)-methylamine hydrochloride; 4-Fluorocyclohexylmethylamine HCl salt
EINECS	Contact for details

Quality Control

Our (4-Fluorocyclohexyl)Methanamine HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.