Description

(S)-1-(2-Chlorophenyl)Ethanamine Hydrochloride is a high-purity chiral amine salt, a key building block in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined intermediate critical for developing enantiomerically pure active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral synthons for complex molecule assembly.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in chiral separation techniques like HPLC.

Basic Information

Product Name	(S)-1-(2-Chlorophenyl)Ethanamine Hydrochloride
CAS No.	1398109-11-9
Molecular Formula	C8H11Cl2N
Molecular Weight	192.09 g/mol
Synonyms	(S)-1-(2-Chlorophenyl)ethan-1-amine hydrochloride; (S)-α-Methyl-2-chlorobenzylamine hydrochloride; (S)-(-)-1-(2-Chlorophenyl)ethylamine hydrochloride; (S)-2-Chloro-α-methylbenzylamine hydrochloride; (1S)-1-(2-Chlorophenyl)ethanaminium chloride; (S)-1-(o-Chlorophenyl)ethylamine HCl
EINECS	Contact for details

Quality Control

Our (S)-1-(2-Chlorophenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical-grade intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.