Description

6-(tert-Butylsulfonyl)-4-Chloro-7-Methoxyquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline core functionalized with a sulfonyl and chloro-methoxy substitution pattern. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of oncology and anti-infectives.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds due to its reactive chloro and sulfonyl groups.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Investigated for use in the synthesis of organic electronic materials and functional dyes.

Basic Information

Product Name	6-(tert-Butylsulfonyl)-4-Chloro-7-Methoxyquinoline
CAS No.	1398054-55-1
Molecular Formula	C₁₄H₁₆ClNO₃S
Molecular Weight	313.80 g/mol
Synonyms	4-Chloro-7-methoxy-6-[(2-methylpropan-2-yl)sulfonyl]quinoline; 4-Chloro-6-(tert-butylsulfonyl)-7-methoxyquinoline; 6-(tert-Butylsulfonyl)-4-chloro-7-methoxyquinoline; 1398054-55-1; Quinoline, 4-chloro-7-methoxy-6-[(2-methyl-2-propanyl)sulfonyl]-; 4-Chloro-7-methoxy-6-(2-methyl-2-propanylsulfonyl)quinoline
EINECS	Contact for details

Quality Control

Our 6-(tert-Butylsulfonyl)-4-Chloro-7-Methoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.