Description

2-Bromo-6-(cyclopropylamino)nitrobenzene, also known as N-(3-Bromo-2-nitrophenyl)cyclopropylamine, is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated nitrobenzene structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific bromo and nitro functional groups enable key coupling and cyclization reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its nitroaromatic scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the cyclopropylamine moiety.
• Academic & Industrial R&D: Essential for methodological studies and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Bromo-6-(Cyclopropylamino)Nitrobenzene, N-(3-Bromo-2-Nitrophenyl)Cyclopropylamine
CAS No.	1396554-46-3
Molecular Formula	C9H9BrN2O2
Molecular Weight	257.09 g/mol
Synonyms	N-(3-Bromo-2-nitrophenyl)cyclopropanamine; 1-Bromo-2-nitro-3-(cyclopropylamino)benzene; 2-Nitro-6-bromo-N-cyclopropylaniline; 3-Bromo-2-nitro-N-cyclopropylaniline; Cyclopropanamine, N-(3-bromo-2-nitrophenyl)-; 2-Bromo-6-(cyclopropylamino)nitrobenzene; 2-Bromo-6-nitro-N-cyclopropylaniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(cyclopropylamino)nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.