Description

8-Bromo-5-Fluoro-3-Iodo-Quinolin-4-Ol CAS NO 1395493-17-0 is a highly functionalized quinoline derivative, a key building block in advanced organic synthesis. Its multi-halogenated structure makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by acting as a core scaffold for bioactive molecules.
• Material Science: A building block for creating organic semiconductors, OLED materials, and liquid crystals due to its halogen-substituted quinoline core.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry and proteomics research.
• Catalyst Ligand Synthesis: Utilized to prepare complex nitrogen-containing ligands for transition metal catalysis.
• Academic & Contract Research: Essential for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-5-Fluoro-3-Iodo-Quinolin-4-Ol
CAS No.	1395493-17-0
Molecular Formula	C9H4BrFINO
Molecular Weight	367.94 g/mol
Synonyms	4-Quinolinol, 8-bromo-5-fluoro-3-iodo-; 8-Bromo-5-fluoro-3-iodo-4-quinolinol; 8-Bromo-5-fluoro-3-iodoquinolin-4-ol; 5-Fluoro-8-bromo-3-iodoquinolin-4-ol; 3-Iodo-8-bromo-5-fluoroquinolin-4-ol; 1395493-17-0; 8-Br-5-F-3-I-quinolin-4-ol
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoro-3-Iodo-Quinolin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.