Description

Methyl 3-Bromo-4-Oxo-1,4-Dihydroquinoline-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core structure. This compound is essential for medicinal chemistry research and development, serving as a critical building block for synthesizing novel drug candidates with targeted biological activity. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and further functionalization to create diverse chemical libraries.
• Agrochemical Research: Potential intermediate for developing new crop protection agents and pesticides.
• Material Science: Investigated as a precursor for organic electronic materials and functional dyes.

Basic Information

Product Name	Methyl 3-Bromo-4-Oxo-1,4-Dihydroquinoline-8-Carboxylate
CAS No.	1395493-15-8
Molecular Formula	C11H8BrNO3
Molecular Weight	282.09 g/mol
Synonyms	Methyl 3-bromo-4-oxo-1,4-dihydroquinoline-8-carboxylate; 8-Quinolinecarboxylic acid, 3-bromo-1,4-dihydro-4-oxo-, methyl ester; 3-Bromo-4-hydroxyquinoline-8-carboxylic acid methyl ester; 3-Bromo-1,4-dihydro-4-oxoquinoline-8-carboxylic acid methyl ester; Methyl 3-bromo-4-hydroxyquinoline-8-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-4-Oxo-1,4-Dihydroquinoline-8-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.