Description

8-Bromo-5-Fluoro-3-Iodoquinolin-4(1H)-One is a high-purity, multi-halogenated quinolinone derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a valuable scaffold for developing novel pharmaceutical compounds and functional materials. This intermediate is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for targeted molecular construction.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Building block for creating organic electronic materials and advanced polymers with specific optoelectronic properties.
• Chemical Biology: Probe or linker molecule in the study of biological pathways and protein interactions.
• Organic Synthesis: Versatile substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) and further functionalization due to its reactive halogen sites.

Basic Information

Product Name	8-Bromo-5-Fluoro-3-Iodoquinolin-4(1H)-One
CAS No.	1395493-10-3
Molecular Formula	C9H4BrFINO
Molecular Weight	367.94 g/mol
Synonyms	8-Bromo-5-fluoro-3-iodo-1,4-dihydroquinolin-4-one; 8-Bromo-5-fluoro-3-iodoquinolin-4-ol; 4(1H)-Quinolinone, 8-bromo-5-fluoro-3-iodo-; 1395493-10-3; 8-Br-5-F-3-I-quinolin-4-one
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoro-3-Iodoquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.