Description

Methyl 3-Bromo-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core structure. This compound is of significant value for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds due to its reactive bromine and ester functional groups.
• Agrochemical Research: Potential application in the development of new active ingredients for crop protection, leveraging its heterocyclic structure.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening to discover new biologically active molecules.

Basic Information

Product Name	Methyl 3-Bromo-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
CAS No.	1395493-07-8
Molecular Formula	C11H8BrNO3
Molecular Weight	282.09 g/mol
Synonyms	Methyl 3-bromo-4-oxo-1,4-dihydroquinoline-6-carboxylate; 3-Bromo-4-oxo-1,4-dihydroquinoline-6-carboxylic acid methyl ester; 6-Quinolinecarboxylic acid, 3-bromo-1,4-dihydro-4-oxo-, methyl ester; 3-Bromo-4-hydroxyquinoline-6-carboxylic acid methyl ester; Methyl 3-bromo-4-hydroxyquinoline-6-carboxylate; 3-Bromo-4-oxo-1H-quinoline-6-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We are committed to meeting the exacting standards required for pharmaceutical R&D and can support custom synthesis under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.