Description

8-Bromo-3-Iodoquinolin-4(1H)-One is a high-purity, multi-halogenated quinolinone derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique halogenated structure, which provides versatile reactive sites for constructing complex heterocyclic frameworks. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active quinoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to create complex molecular architectures.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for metal-organic frameworks (MOFs), and functional dyes due to the quinolinone core.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study biological pathways and enzyme functions.

Basic Information

Item	Detail
Product Name	8-Bromo-3-Iodoquinolin-4(1H)-One
CAS No.	1395493-03-4
Molecular Formula	C9H5BrINO
Molecular Weight	349.95 g/mol
Synonyms	4(1H)-Quinolinone, 8-bromo-3-iodo-; 8-Bromo-3-iodo-1,4-dihydroquinolin-4-one; 8-Bromo-3-iodoquinolin-4-ol; 3-Iodo-8-bromoquinolin-4(1H)-one; 8-Br-3-I-quinolin-4-one
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Iodoquinolin-4(1H)-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.