Description

tert-Butyl 5,6,7,8-Tetrahydroquinoline-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in the construction of complex heterocyclic scaffolds for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides with specific biological activity.
• Organic Synthesis: Utilized in multi-step synthetic routes to introduce the tetrahydroquinoline moiety, a privileged structure in bioactive compounds.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	tert-Butyl 5,6,7,8-Tetrahydroquinoline-8-Carboxylate
CAS No.	1395492-98-4
Molecular Formula	C₁₄H₁₉NO₂
Molecular Weight	233.31 g/mol
Synonyms	8-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydroquinoline; tert-Butyl 5,6,7,8-tetrahydro-8-quinolinecarboxylate; 5,6,7,8-Tetrahydroquinoline-8-carboxylic acid tert-butyl ester; 8-Quinolinecarboxylic acid, 5,6,7,8-tetrahydro-, 1,1-dimethylethyl ester; THQ-Carboxylate tert-Butyl ester; BOC-THQ-8-COOtBu
EINECS	Contact for details

Quality Control

Our tert-Butyl 5,6,7,8-Tetrahydroquinoline-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.