Description

Methyl 3-Iodo-4-Oxo-1,4-Dihydroquinoline-8-Carboxylate is a high-value, halogenated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine substituent and a carboxylate ester, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinoline scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging its halogenated heterocyclic structure.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, organic semiconductors, or metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or labeling reagent due to the reactivity of the iodine atom, which can be used in cross-coupling reactions or as a radiolabeling site.
• Academic & R&D: Fundamental building block in methodological organic chemistry research for studying new catalytic reactions, such as Suzuki-Miyaura or Sonogashira couplings.
• Ligand Synthesis: Potential precursor for creating novel chelating ligands used in catalysis or metal complexation studies.

Basic Information

Product Name	Methyl 3-Iodo-4-Oxo-1,4-Dihydroquinoline-8-Carboxylate
CAS No.	1395492-97-3
Molecular Formula	C11H8INO3
Molecular Weight	329.09 g/mol
Synonyms	Methyl 3-iodo-4-oxo-1,4-dihydroquinoline-8-carboxylate; 8-Quinolinecarboxylic acid, 1,4-dihydro-3-iodo-4-oxo-, methyl ester; 3-Iodo-4-oxo-1,4-dihydroquinoline-8-carboxylic acid methyl ester; Methyl 3-iodo-1,4-dihydro-4-oxoquinoline-8-carboxylate; 1395492-97-3; Methyl 3-iodoquinoline-8-carboxylate-4-one
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Iodo-4-Oxo-1,4-Dihydroquinoline-8-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.