Description

1-(2,5-Dichloro-Phenyl)-Ethylamine Hydrochloride is a high-purity organic intermediate, primarily valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. Its significance lies in providing a chiral amine moiety with a substituted phenyl ring, enabling the construction of molecules with specific biological activity. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the dichlorophenyl group contributes to bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency of stereoselective synthetic routes.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and constructing molecular libraries.
• Fine Chemical Production: Integral to the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	1-(2,5-Dichloro-Phenyl)-Ethylamine Hydrochloride
CAS No.	1394838-41-5
Molecular Formula	C8H10Cl3N
Molecular Weight	226.53 g/mol
Synonyms	(1-(2,5-Dichlorophenyl)ethyl)amine hydrochloride; α-Methyl-2,5-dichlorobenzeneethanamine hydrochloride; 2,5-Dichloro-α-methylbenzeneethanamine hydrochloride; (R/S)-1-(2,5-Dichlorophenyl)ethylamine HCl; 1-(2,5-Dichlorophenyl)ethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2,5-Dichloro-Phenyl)-Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.