Description

3-Benzyl-3-Azabicyclo[3.1.0]Hexan-6-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1394662-71-5. This bicyclic amine derivative is a critical building block in modern medicinal chemistry, valued for its unique structural framework that enables the synthesis of novel bioactive compounds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and other targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery and development.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecular architectures in lead optimization and structure-activity relationship (SAR) studies.
• CNS Drug Development: Used in the research and synthesis of potential therapeutic agents targeting neurological and psychiatric disorders.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Supports route scouting and process development from laboratory to pilot plant scale for new chemical entities.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3-Benzyl-3-Azabicyclo[3.1.0]Hexan-6-Amine Dihydrochloride
CAS No.	1394662-71-5
Molecular Formula	C12H18Cl2N2
Molecular Weight	261.19 g/mol
Synonyms	3-Benzyl-3-azabicyclo[3.1.0]hexan-6-amine dihydrochloride; 3-Benzyl-3-azabicyclo[3.1.0]hexan-6-amine hydrochloride (1:2); 6-Amino-3-benzyl-3-azabicyclo[3.1.0]hexane dihydrochloride; 3-Benzyl-3-azabicyclo[3.1.0]hexan-6-amine, dihydrochloride; Bicyclo[3.1.0]hexan-6-amine, 3-(phenylmethyl)-3-aza-, hydrochloride (1:2); 1394662-71-5; 3-Benzyl-3-azabicyclo[3.1.0]hexan-6-amine HCl salt
EINECS	Contact for details

Quality Control

Our 3-Benzyl-3-Azabicyclo[3.1.0]Hexan-6-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.