Description

2-Bromo-6-Fluoro-4-Methylphenol is a halogenated phenolic compound that serves as a versatile and valuable synthetic intermediate. Its molecular structure, featuring bromine and fluorine substituents on the phenol ring, makes it a critical building block for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, where the halogenated phenol core contributes to bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and brominated aromatic units used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification Agent: Employed to introduce halogenated phenolic groups into polymer chains to alter properties like flame retardancy, thermal stability, and solubility.
• Ligand & Catalyst Development: Useful in organometallic chemistry for creating novel ligands and catalysts used in cross-coupling reactions and other catalytic processes.
• Chemical Research & Development: A high-purity reagent for method development, structure-activity relationship (SAR) studies, and exploratory synthesis in academic and industrial R&D labs.

Basic Information

Product Name	2-Bromo-6-Fluoro-4-Methylphenol
CAS No.	1394291-51-0
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	4-Methyl-2-bromo-6-fluorophenol; 6-Fluoro-2-bromo-4-methylphenol; 2-Bromo-6-fluoro-p-cresol; Phenol, 2-bromo-6-fluoro-4-methyl-; 2-Br-6-F-4-Me-PhOH
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Fluoro-4-Methylphenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.