Description

5-Chloro-6-Fluoro-8-Quinolinamine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated quinoline structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, antimicrobial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probe: Utilized as a core structure for designing fluorescent probes and molecular tags for biological imaging and diagnostic applications.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and contract research organizations (CROs).

Basic Information

Item	Details
Product Name	5-Chloro-6-Fluoro-8-Quinolinamine
CAS No.	1394083-91-0
Molecular Formula	C9H6ClFN2
Molecular Weight	196.61 g/mol
Synonyms	8-Amino-5-chloro-6-fluoroquinoline; 5-Chloro-6-fluoroquinolin-8-amine; 5-Chloro-6-fluoro-8-aminoquinoline; 1394083-91-0; Quinolinamine, 5-chloro-6-fluoro-; 6-Fluoro-5-chloro-8-quinolinamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Fluoro-8-Quinolinamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.