Description

6-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylic Acid is a high-purity, functionalized benzothiophene derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique heterocyclic core enables the creation of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing target molecules with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzothiophene scaffold.
• Material Science: Serves as a monomer or functional additive in the research of organic semiconductors, conductive polymers, and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of protein interactions and enzyme mechanisms due to its reactive carboxylic acid and hydroxyl groups.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized heterocyclic dyes and optical brighteners.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting fundamental research in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	6-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	1393803-55-8
Molecular Formula	C9H5ClO3S
Molecular Weight	228.65 g/mol
Synonyms	6-Chloro-3-hydroxy-1-benzothiophene-2-carboxylic acid; 6-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid; 2-Benzothiophenecarboxylic acid, 6-chloro-3-hydroxy-; 3-Hydroxy-6-chlorobenzo[b]thiophene-2-carboxylic acid; 6-Chloro-3-hydroxybenzo[b]thien-2-carboxylic acid; 6-Chloro-3-hydroxy-2-benzothiophenecarboxylic acid; 6-Chloro-3-hydroxy-2-carboxybenzothiophene
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.