Description

3-(4-Bromophenyl)Oxetane-3-Carboxylic Acid is a high-purity, synthetically valuable oxetane derivative, serving as a crucial chiral building block in advanced organic synthesis. Its unique oxetane ring fused with a brominated aromatic carboxylic acid structure makes it an essential intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where the oxetane moiety can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials, where the bromophenyl group allows for further cross-coupling reactions.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags to study biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Item	Detail
Product Name	3-(4-Bromophenyl)Oxetane-3-Carboxylic Acid
CAS No.	1393585-20-0
Molecular Formula	C10H9BrO3
Molecular Weight	257.08 g/mol
Synonyms	3-(4-Bromophenyl)oxetane-3-carboxylic acid; 3-(p-Bromophenyl)oxetane-3-carboxylic acid; 4-Bromo-alpha,α-dimethylbenzenepropanoic acid, oxetane analog; 1-Oxaspiro[2.3]hexane-1-carboxylic acid, 5-(4-bromophenyl)-; 5-(4-Bromophenyl)-1-oxaspiro[2.3]hexane-1-carboxylic acid; BPOA; 3-Carboxy-3-(4-bromophenyl)oxetane
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Bromophenyl)Oxetane-3-Carboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material typically meets a purity specification of ≥97% (HPLC). A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with each shipment, ensuring full traceability and compliance with your R&D or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.