Description

2-Amino-6-Fluoroisonicotinic Acid is a high-purity fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both amino and carboxylic acid functionalities onto a fluorinated heterocyclic core, enabling precise chemical modifications. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in kinase inhibitor and antibiotic research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Useful as a probe or labeling reagent due to its reactive amine and acid groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and library synthesis for high-throughput screening.

Basic Information

Product Name	2-Amino-6-Fluoroisonicotinic Acid
CAS No.	1393583-50-0
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	6-Fluoro-2-aminopyridine-4-carboxylic acid; 2-Amino-6-fluoropyridine-4-carboxylic acid; 4-Carboxy-6-fluoro-2-aminopyridine; 6-Fluoro-2-aminoisonicotinic acid; 2-Amino-6-fluoro-4-pyridinecarboxylic acid; FAIPA (abbreviation); 4-Pyridinecarboxylic acid, 2-amino-6-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Fluoroisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.