Description

3-(3-Iodophenyl)Oxetan-3-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique oxetane amine scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with potential therapeutic applications. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates, particularly in oncology and CNS disorders.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in targeted protein degradation platforms.
• Covalent Inhibitor Synthesis: The iodine substituent allows for further functionalization via cross-coupling reactions to create targeted covalent inhibitors.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	3-(3-Iodophenyl)Oxetan-3-Amine Hydrochloride
CAS No.	1393560-26-3
Molecular Formula	C9H11ClINO
Molecular Weight	311.55 g/mol
Synonyms	3-Amino-3-(3-iodophenyl)oxetane hydrochloride; 3-(3-Iodophenyl)-3-oxetanamine hydrochloride; 3-(3-Iodophenyl)oxetan-3-amine HCl; 3-Iodophenyl oxetan-3-amine hydrochloride; Oxetan-3-amine, 3-(3-iodophenyl)-, hydrochloride; 1393560-26-3
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Iodophenyl)Oxetan-3-Amine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.