Description

5-(Oxan-4-Yloxy)Pyridine-2-Carboxylic Acid CAS NO 1393330-58-9 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine-carboxylic acid scaffold with a tetrahydro-2H-pyran-4-yloxy substituent. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Employed in the development of complex ligands for catalysis or as chelating agents in metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: Serves as a building block for the production of specialty chemicals, agrochemicals, and other high-value organic compounds.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for exploratory synthetic chemistry and method development.

Basic Information

Product Name	5-(Oxan-4-Yloxy)Pyridine-2-Carboxylic Acid
CAS No.	1393330-58-9
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	5-[(Tetrahydro-2H-pyran-4-yl)oxy]pyridine-2-carboxylic acid; 5-(Oxan-4-yloxy)picolinic acid; 5-(Tetrahydropyran-4-yloxy)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 5-[(tetrahydro-2H-pyran-4-yl)oxy]-; 1393330-58-9; 5-(THP-4-yloxy)picolinic acid; 5-(Oxan-4-yloxy)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Oxan-4-Yloxy)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and other relevant analytical methods. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.