Description

6-Oxa-2-Aza-Spiro[3.4]Octane Hemioxalate is a high-value, nitrogen-oxygen containing spirocyclic building block with the CAS registry number 1392804-58-8. This compound is a critical intermediate in modern pharmaceutical research and development, prized for its unique three-dimensional structure that enables the synthesis of novel, complex molecular architectures. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients with improved properties.

Application

• Pharmaceutical Intermediate: A key scaffold for constructing novel drug candidates, particularly in central nervous system (CNS), antiviral, and anti-infective therapeutic areas.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) explorations to optimize potency, selectivity, and pharmacokinetic profiles of lead compounds.
• Process Chemistry & Scale-Up: Serves as a defined starting material or advanced intermediate in the development of robust, scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Employed in the discovery and synthesis of new generation herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Useful for creating tool compounds and molecular probes to study biological pathways and target validation.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental organic synthesis research and custom synthesis projects.

Basic Information

Product Name	6-Oxa-2-Aza-Spiro[3.4]Octane Hemioxalate
CAS No.	1392804-58-8
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	6-Oxa-2-azaspiro[3.4]octane hemioxalate; 2-Aza-6-oxaspiro[3.4]octane hemioxalate; Spiro[3.4]octane-2,6-diazine hemioxalate (related); 1392804-58-8; 6-Oxa-2-azaspiro[3.4]octane oxalic acid salt (1:0.5); Azaspirocyclic building block hemioxalate; Oxa-aza spirooctane salt
EINECS	Contact for details

Quality Control

Our 6-Oxa-2-Aza-Spiro[3.4]Octane Hemioxalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.