Description

3-Methoxyazetidine-3-Methanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its unique azetidine scaffold, which is increasingly important in modern medicinal chemistry for designing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its constrained azetidine ring system.
• CNS Drug Discovery: Serves as a precursor for compounds being investigated for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate for the development of new active ingredients with novel modes of action.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.

Basic Information

Product Name	3-Methoxyazetidine-3-Methanamine Dihydrochloride
CAS No.	1392803-43-8
Molecular Formula	C5H13Cl2N2O
Molecular Weight	185.07 g/mol
Synonyms	3-(Aminomethyl)-3-methoxyazetidine dihydrochloride; 3-Methoxy-3-(aminomethyl)azetidine hydrochloride (1:2); 3-Methoxyazetidine-3-methylamine dihydrochloride; 3-(Aminomethyl)-3-methoxy-azetidine dihydrochloride; 3-Methoxy-3-azetidinemethanamine dihydrochloride; Azetidine, 3-(aminomethyl)-3-methoxy-, dihydrochloride; 3-Methoxy-3-(aminomethyl)azetidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-Methoxyazetidine-3-Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.