Description

trans-3-Aminocyclopentane-1-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant building block used in the synthesis of complex molecules. This compound is valued for its rigid, functionalized cyclopentane scaffold, which is crucial for modulating the biological activity and physicochemical properties of drug candidates. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetics & Constrained Analogs: Used to introduce conformational restraint into peptide backbones, enhancing stability, potency, and selectivity.
• Ligand Synthesis: Serves as a precursor for catalysts and chiral ligands in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and receptor interactions.
• Academic & Contract Research: Employed in university and CRO settings for exploratory synthetic chemistry and methodology development.
• Custom Synthesis Building Block: A starting material for the contract manufacturing of specialized fine chemicals and reference standards.

Basic Information

Product Name	trans-3-Aminocyclopentane-1-Carboxylic Acid Hydrochloride
CAS No.	1392803-15-4
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	(1R,3S)-3-Aminocyclopentane-1-carboxylic acid hydrochloride; (1S,3R)-3-Aminocyclopentane-1-carboxylic acid hydrochloride; trans-3-ACPC HCl; 3-Amino-1-cyclopentanecarboxylic acid hydrochloride (trans); (1R,3S)-3-Aminocyclopentanecarboxylic acid hydrochloride; (1S,3R)-3-Aminocyclopentanecarboxylic acid hydrochloride; 3-ACPC HCl; Cyclopentane-1-carboxylic acid, 3-amino-, hydrochloride, (1R,3S)-rel-
EINECS	Contact for details

Quality Control

Our trans-3-Aminocyclopentane-1-Carboxylic Acid Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, chiral purity, and identity confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.