Description

6-Bromo-3-Chloro-2-Methylquinoxaline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique halogenated quinoxaline core, which serves as a versatile scaffold for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinases and other enzymes, due to the quinoxaline pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the halogenated methylquinoxaline structure can impart specific biological activity.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce diverse functional groups.
• Library Synthesis: A valuable scaffold for generating focused compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	6-Bromo-3-Chloro-2-Methylquinoxaline
CAS No.	1392413-56-7
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	6-Bromo-3-chloro-2-methylquinoxaline; 2-Methyl-6-bromo-3-chloroquinoxaline; Quinoxaline, 6-bromo-3-chloro-2-methyl-; 3-Chloro-6-bromo-2-methylquinoxaline; 6-Bromo-3-chloro-2-methyl-quinoxaline; 1392413-56-7
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-2-Methylquinoxaline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.