Description

6-Fluoro-4H-Furo[3,2-B]Pyrrole-5-Carboxylic Acid Ethyl Ester is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused furopyrrole scaffold introduces valuable structural complexity. Pharmaceutical research and development (R&D) teams, as well as agrochemical innovators, need this precise chemical to explore new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom and heterocyclic core enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a specialized monomer or precursor for advanced organic electronic materials, such as organic semiconductors or light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	6-Fluoro-4H-Furo[3,2-B]Pyrrole-5-Carboxylic Acid Ethyl Ester
CAS No.	1392272-60-4
Molecular Formula	C9H8FNO3
Molecular Weight	197.16 g/mol
Synonyms	Ethyl 6-Fluoro-4H-furo[3,2-b]pyrrole-5-carboxylate; 4H-Furo[3,2-b]pyrrole-5-carboxylic acid, 6-fluoro-, ethyl ester; 6-Fluoro-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester; Furo[3,2-b]pyrrole-5-carboxylic acid, 6-fluoro-4H-, ethyl ester; 1392272-60-4; Ethyl 6-fluoro-4H-furo[3,2-b]pyrrole-5-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4H-Furo[3,2-B]Pyrrole-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.