Description

2-(4-(6-Aminopyrimidin-4-Yl)Piperazin-1-Yl)Ethanol is a high-purity, functionalized piperazine-pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D teams and contract research organizations (CROs) engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• Bioconjugation & Probe Development: The ethanol linker and reactive amine group enable its use in creating fluorescent probes or affinity labels for biochemical studies.
• Agrochemical Synthesis: Potential intermediate in the development of novel crop protection chemicals with specific biological activity.
• Academic Research: Used in universities and research institutes for studying structure-activity relationships (SAR) and heterocyclic chemistry.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) specializing in custom API synthesis from gram to kilogram scale.

Basic Information

Item	Details
Product Name	2-(4-(6-Aminopyrimidin-4-Yl)Piperazin-1-Yl)Ethanol
CAS No.	1392236-38-2
Molecular Formula	C10H16N6O
Molecular Weight	236.27 g/mol
Synonyms	2-[4-(6-Aminopyrimidin-4-yl)piperazin-1-yl]ethanol; 4-(6-Amino-4-pyrimidinyl)-1-piperazineethanol; 6-Amino-4-(1-piperazinyl)pyrimidine-1-ethanol; 2-(4-(6-Aminopyrimidin-4-yl)piperazin-1-yl)ethan-1-ol; 1392236-38-2; 2-(4-(6-Aminopyrimidin-4-yl)piperazin-1-yl)ethyl alcohol
EINECS	Contact for details

Quality Control

Our production of 2-(4-(6-Aminopyrimidin-4-Yl)Piperazin-1-Yl)Ethanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, identity confirmation via spectroscopic methods, and control of specified impurities. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.