Description

(S)-6-Methylchroman-4-Amine Hydrochloride CAS NO 1392218-82-4 is a high-purity chiral amine derivative, a key building block in advanced pharmaceutical synthesis. Its value lies in its role as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production teams in pharmaceutical development, agrochemical research, and specialty chemical manufacturing seeking to create enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry is vital for bioactivity and environmental safety.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for stereoselective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring precise molecular architecture.
• Academic & Industrial Research: A valuable reference standard and starting material for medicinal chemistry programs and process chemistry optimization in R&D laboratories.

Basic Information

Product Name	(S)-6-Methylchroman-4-Amine Hydrochloride
CAS No.	1392218-82-4
Molecular Formula	C10H14ClNO
Molecular Weight	199.68 g/mol
Synonyms	(4S)-6-Methyl-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; (S)-6-Methyl-3,4-dihydro-2H-chromen-4-amine hydrochloride; (S)-6-Methylchroman-4-amine HCl; 4-Amino-6-methylchroman hydrochloride (S-enantiomer); (S)-4-Amino-6-methylchroman hydrochloride; 1392218-82-4; (S)-Toloxatone intermediate derivative
EINECS	Contact for details

Quality Control

Our (S)-6-Methylchroman-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.