Description

1-Amino-Cyclobutanemethanol Hcl is a high-purity organic building block and chiral intermediate of significant interest in advanced chemical synthesis. Its value lies in its unique cyclobutane scaffold, which is increasingly sought after for constructing novel molecular architectures with specific three-dimensional properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications in medicinal chemistry and the synthesis of complex active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space due to its strained cyclobutane ring.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with potentially improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Research: Employed as a probe or precursor in the synthesis of molecular tools for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1-Amino-Cyclobutanemethanol Hcl
CAS No.	1392213-15-8
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(1-Aminocyclobutyl)methanol hydrochloride; 1-(Aminomethyl)cyclobutanol hydrochloride; Cyclobutanemethanol, 1-amino-, hydrochloride; 1-Aminocyclobutanemethanol hydrochloride; (1-Aminocyclobutyl)methanol HCl; Aminocyclobutanemethanol HCl; 1-Amino-1-(hydroxymethyl)cyclobutane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Amino-Cyclobutanemethanol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.