Description

5-(tert-Butoxycarbonyl)-1-Methyl-4,5,6,7-Tetrahydro-1H-[1,2,3]Triazolo[4,5-C]Pyridine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex fused triazolopyridine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors working on innovative drug discovery programs, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those containing the privileged triazolopyridine heterocycle.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Process Chemistry Development: Serves as a critical raw material for optimizing scalable and cost-effective synthetic routes to target molecules under Good Manufacturing Practice (GMP) conditions.
• API Synthesis: Integral in the construction of final Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trial material production.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for further derivatization, making it suitable for creating chemical probes or tagged molecules for biological studies.

Basic Information

Product Name	5-(tert-Butoxycarbonyl)-1-Methyl-4,5,6,7-Tetrahydro-1H-[1,2,3]Triazolo[4,5-C]Pyridine-7-Carboxylic Acid
CAS No.	1391733-57-5
Molecular Formula	C14H20N4O4
Molecular Weight	308.33 g/mol
Synonyms	1-Methyl-5-[(2-methylpropan-2-yl)oxycarbonyl]-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-7-carboxylic acid; 5-Boc-1-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-7-carboxylic acid; 1-Methyl-5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-7-carboxylic acid; tert-Butyl 7-carboxy-1-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5-carboxylate; BOC-Protected Triazolopyridine Carboxylic Acid; CAS 1391733-57-5
EINECS	Contact for details

Quality Control

Our 5-(tert-Butoxycarbonyl)-1-Methyl-4,5,6,7-Tetrahydro-1H-[1,2,3]Triazolo[4,5-C]Pyridine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.