Description

(R)-1-(3-Bromophenyl)-2-Methylpropan-1-Amine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, where stereochemical purity is paramount. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries for creating novel therapeutic candidates and optimizing synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel central nervous system (CNS) agents and other therapeutic molecules.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical transformations to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for metal-catalyzed reactions, such as asymmetric hydrogenation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry: Integral to scaling up and optimizing synthetic pathways for cost-effective and robust API manufacturing.

Basic Information

Product Name	(R)-1-(3-Bromophenyl)-2-Methylpropan-1-Amine Hydrochloride
CAS No.	1391566-64-5
Molecular Formula	C10H14BrN • HCl
Molecular Weight	264.59 g/mol (Free base: 228.13 g/mol)
Synonyms	(R)-1-(3-Bromophenyl)-2-methylpropan-1-amine HCl; (R)-3-Bromo-α-isobutylbenzylamine hydrochloride; (R)-1-(3-Bromophenyl)-2-methylpropylamine hydrochloride; (R)-3'-Bromo-α-isobutylbenzylamine HCl; (R)-3-Bromo-α-methylbenzeneethanamine hydrochloride; (R)-1-(3-Bromophenyl)-2-methyl-1-propanamine hydrochloride; (R)-3-Bromophenylisobutylamine HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Bromophenyl)-2-Methylpropan-1-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.