Description

(R)-2-(3-Bromophenyl)Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of novel therapeutics, including central nervous system (CNS) agents and receptor-targeted drugs.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the asymmetric synthesis of potential drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis.
• API Development: Building block for the synthesis of enantiopure Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Used in pharmacological research as a standard or probe for studying specific biological pathways.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	(R)-2-(3-Bromophenyl)Pyrrolidine Hydrochloride
CAS No.	1391550-13-2
Molecular Formula	C10H12BrN•HCl
Molecular Weight	262.57 g/mol (Free base: 226.11 g/mol)
Synonyms	(R)-2-(3-Bromophenyl)pyrrolidine HCl; (R)-3-Bromo-α-(pyrrolidin-2-yl)benzene hydrochloride; (R)-2-(3-Bromophenyl)-1-azacyclopentane hydrochloride; (R)-2-(m-Bromophenyl)pyrrolidine hydrochloride; (R)-NSC 781106 Hydrochloride; Pyrrolidine, 2-(3-bromophenyl)-, (2R)-, hydrochloride; (2R)-2-(3-Bromophenyl)pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-(3-Bromophenyl)Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.