Description

(1S)-2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propylamine Hydrochloride is a high-purity chiral amine hydrochloride salt, a critical building block in modern organic synthesis. Its value lies in its well-defined stereochemistry and the presence of the trifluoromethyl group, which is instrumental for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients requiring specific stereochemical configurations and enhanced metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced herbicides and pesticides, where the trifluoromethyl group often enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that benefit from its specific aromatic and fluorinated structure.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	(1S)-2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propylamine Hydrochloride
CAS No.	1391546-16-9
Molecular Formula	C11H14F3N·HCl
Molecular Weight	253.69 g/mol
Synonyms	(1S)-1-[4-(Trifluoromethyl)phenyl]-2-methylpropylamine hydrochloride; (S)-1-(4-(Trifluoromethyl)phenyl)-2-methylpropan-1-amine hydrochloride; (S)-α-Methyl-4-(trifluoromethyl)benzenepropanamine hydrochloride; (S)-2-Methyl-1-[4-(trifluoromethyl)phenyl]propan-1-amine hydrochloride; (S)-1-(4-Trifluoromethylphenyl)-2-methylpropylamine HCl; Benzenepropanamine, α-methyl-4-(trifluoromethyl)-, (αS)-, hydrochloride
EINECS	Contact for details

Quality Control

Our (1S)-2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.