Description

(S)-2-Amino-2-(4-Bromophenyl)Acetic Acid Hydrochloride is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its core value lies in providing a stereochemically defined, functionalized aromatic scaffold essential for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Peptidomimetic Synthesis: Used to incorporate a constrained, bromo-substituted phenylglycine moiety into peptide analogs to modulate biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed as a building block in the synthesis of advanced, optically active pesticides and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring a specific enantiomer of a brominated amino acid derivative.

Basic Information

Product Name	(S)-2-Amino-2-(4-Bromophenyl)Acetic Acid Hydrochloride
CAS No.	1391529-06-8
Molecular Formula	C8H9BrClNO2
Molecular Weight	266.52 g/mol
Synonyms	(S)-4-Bromophenylglycine Hydrochloride; (S)-2-Amino-2-(4-bromophenyl)ethanoic acid hydrochloride; (S)-α-Amino-4-bromobenzeneacetic acid hydrochloride; L-4-Bromophenylglycine HCl; (S)-4-Bromo-DL-phenylglycine hydrochloride; (S)-Amino(4-bromophenyl)acetic acid hydrochloride; (2S)-2-Amino-2-(4-bromophenyl)acetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-2-(4-Bromophenyl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.