Description

(S)-Methyl 2-Amino-2-(4-Bromophenyl)Acetate Hcl CAS NO 1391528-74-7 is a high-purity chiral building block, specifically the hydrochloride salt of a phenylglycine derivative. This compound is a critical intermediate for the synthesis of enantiomerically pure pharmaceuticals and advanced organic molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiopure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the study and development of novel asymmetric catalytic reactions.
• Peptidomimetics & Bioactive Molecule Design: Employed in medicinal chemistry for constructing complex molecular architectures that mimic peptide structures.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists exploring new reaction pathways and novel chemical entities.

Basic Information

Product Name	(S)-Methyl 2-Amino-2-(4-Bromophenyl)Acetate Hydrochloride
CAS No.	1391528-74-7
Molecular Formula	C9H11BrNO2 • HCl
Molecular Weight	294.55 g/mol (Free base: 258.10 g/mol)
Synonyms	(S)-Methyl 2-Amino-2-(4-bromophenyl)acetate hydrochloride; (S)-Methyl α-Amino-4-bromobenzeneacetate hydrochloride; (S)-Methyl (4-Bromophenyl)glycinate hydrochloride; (S)-Methyl 2-Amino-(4-bromophenyl)acetate HCl; (S)-4-Bromo-DL-phenylglycine methyl ester hydrochloride; (S)-Methyl 2-Amino-2-(p-bromophenyl)acetate hydrochloride; (S)-Methyl 4-Bromophenylglycinate hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-Amino-2-(4-Bromophenyl)Acetate Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.