Description

(S)-3-(p-Tolyl)Morpholine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in asymmetric synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a chiral ligand or auxiliary in catalytic reactions to induce stereoselectivity.
• Agrochemical Research: Serves as a building block for the synthesis of advanced, enantiomerically pure crop protection agents.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for scale-up synthesis.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(S)-3-(p-Tolyl)Morpholine Hydrochloride
CAS No.	1391510-98-7
Molecular Formula	C11H15NO • HCl
Molecular Weight	213.70 g/mol
Synonyms	(S)-3-(4-Methylphenyl)morpholine hydrochloride; (S)-3-(p-Tolyl)morpholine HCl; (S)-3-(4-Tolyl)morpholine hydrochloride; (3S)-3-(4-Methylphenyl)morpholine hydrochloride; (S)-3-(4-Methylphenyl)-morpholine hydrochloride; (S)-3-(p-Methylphenyl)morpholine hydrochloride; (S)-3-(4-Tolyl)-morpholine HCl
EINECS	Contact for details

Quality Control

Our (S)-3-(p-Tolyl)Morpholine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.