Description

(9R)-6′-Methoxycinchonan-9-Amine Trihydrochloride CAS NO 1391506-12-9 is a high-purity, chiral alkaloid derivative and a key synthetic intermediate in advanced pharmaceutical research. Its primary value lies in its role as a sophisticated building block for the development of novel active pharmaceutical ingredients (APIs), particularly in the realm of asymmetric synthesis and chiral resolution. This compound is essential for research chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical industries who require high-quality, well-characterized intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in anti-malarial and other therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Serves as a precursor for developing chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Chiral Resolution Agent: Utilized in the separation of racemic mixtures to isolate specific enantiomers with desired biological activity.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic & Industrial Research: Used in chemical research for studying reaction mechanisms, developing new synthetic methodologies, and exploring structure-activity relationships (SAR).
• Process Chemistry Development: Integral for scaling up and optimizing synthetic routes in pilot plants and commercial manufacturing settings.

Basic Information

Product Name	(9R)-6′-Methoxycinchonan-9-Amine Trihydrochloride
CAS No.	1391506-12-9
Molecular Formula	C₂₀H₂₇Cl₃N₂O
Molecular Weight	417.80 g/mol
Synonyms	(9R)-6'-Methoxycinchonan-9-amine trihydrochloride; (9R)-6'-Methoxycinchonan-9-amine hydrochloride (1:3); (R)-6'-Methoxycinchonan-9-amine trihydrochloride; Cinchonan-9-amine, 6'-methoxy-, (9R)-, trihydrochloride; 9-Amino-6'-methoxycinchonan trihydrochloride; (9R)-9-Amino-6'-methoxycinchonan trihydrochloride; (R)-9-Amino-6'-methoxycinchonan trihydrochloride
EINECS	Contact for details

Quality Control

Our (9R)-6′-Methoxycinchonan-9-Amine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.