Description

(1R,2R)-1,2-Bis(3,5-Dimethylphenyl)-1,2-Ethylenediamine Phosphate is a high-purity chiral diamine phosphate salt, valued for its role as a key ligand and building block in asymmetric synthesis. Its primary commercial significance lies in enabling the production of enantiomerically pure compounds, which are critical for advanced pharmaceutical and agrochemical applications. This product is essential for research institutions and manufacturers in the fine chemical, pharmaceutical, and catalyst development sectors seeking reliable, high-quality chiral auxiliaries.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand or precursor for transition metal catalysts used in hydrogenation, hydrosilylation, and other enantioselective transformations.
• Pharmaceutical Intermediates: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry, such as certain antiviral or cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where the biological activity is highly dependent on molecular handedness.
• Chiral Resolution Agent: Employed to separate racemic mixtures of acids or other compounds through diastereomeric salt formation.
• Material Science Research: Investigated as a component in the synthesis of chiral polymers or metal-organic frameworks (MOFs) with specialized properties.
• Academic & Process R&D: A valuable reagent for method development and discovery chemistry in academic and industrial research laboratories.

Basic Information

Product Name	(1R,2R)-1,2-Bis(3,5-Dimethylphenyl)-1,2-Ethylenediamine Phosphate
CAS No.	1391500-72-3
Molecular Formula	C18H24N2·H3PO4
Molecular Weight	Contact for details
Synonyms	(1R,2R)-(-)-1,2-Bis(3,5-dimethylphenyl)ethylenediamine Phosphate; (R,R)-DMPEDA Phosphate; (1R,2R)-1,2-Bis(3,5-xylyl)ethylenediamine Phosphate; (R,R)-1,2-Bis(3,5-dimethylphenyl)ethane-1,2-diamine Phosphate; (R,R)-DMPEN Phosphate; (1R,2R)-DACH-3,5-Xyl Phosphate; Jacobsen's Ligand Derivative Phosphate Salt
EINECS	Contact for details

Quality Control

Our (1R,2R)-1,2-Bis(3,5-Dimethylphenyl)-1,2-Ethylenediamine Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.